Cold Sores
Cold sores are small blisters that typically appear on or around the lips, caused by the herpes simplex virus (HSV). They can be uncomfortable, unsightly, and may return from time to time, often triggered by stress, illness, or sun exposure.
While cold sores usually clear up on their own, treatment can help speed up healing, reduce discomfort, and lower the risk of passing the virus on to others.
Through 123Meds, you can receive expert-approved treatments for cold sores via our UK-registered online pharmacy service, with prescriptions reviewed by clinicians and delivered discreetly straight to your door.

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Cold sores are small blisters that appear on the lips or around the mouth, caused by the herpes simplex virus (HSV).
There are two types of HSV: HSV-1, which commonly causes oral herpes (cold sores), and HSV-2, which typically causes genital herpes. Cold sores are usually linked to HSV-1 and are easily spread through close contact, such as kissing or sharing items like cutlery, lip balm, razors, or toothbrushes.
Once infected, the HSV-1 virus remains dormant in the body and can reactivate when the immune system is weakened by stress, illness, or fatigue. This can trigger an outbreak of cold sores.
Although cold sores often clear on their own within 7 to 10 days, they can be painful and uncomfortable. Using prescription antiviral treatments, such as Aciclovir or Valaciclovir, can help speed up healing and reduce the severity of symptoms.
At 123Meds, you can access effective cold sore treatments quickly and discreetly through our online consultation service.
Cold sores are most commonly caused by the herpes simplex virus type 1 (HSV-1), although in some cases they can also be triggered by HSV-2.
While HSV-2 is typically linked to genital herpes, it can lead to cold sores through oral transmission, such as during oral sex.
Outbreak frequency varies from person to person. Some people experience cold sores regularly, while others may only have occasional flare-ups. When outbreaks occur, they can be painful and uncomfortable. Antiviral medications, such as Aciclovir or Valaciclovir, are effective at reducing symptoms and helping the sores heal more quickly.
Common cold sore triggers include sun exposure, which can suppress the immune system due to UV radiation, as well as illness, stress, and weakened immunity. Recognising and managing these triggers can help reduce the likelihood of future outbreaks.
At 123Meds, we provide fast, discreet access to clinically approved cold sore treatments through our online consultation service.
Cold sores typically begin with a tingling or burning sensation around the lips or mouth – a common early warning sign of an outbreak.
This is soon followed by the appearance of small, fluid-filled blisters that may feel sore, itchy, or uncomfortable. As the cold sore progresses, the blisters can crack or bleed, making the area particularly painful.
Cold sores usually develop in the following stages:
- A tingling, itching, or burning feeling around the affected area
- Formation of small fluid-filled blisters
- Blisters burst and may leak before crusting over
- A scab forms and gradually heals over the next few days
Starting antiviral treatment early – ideally at the tingling stage – can help reduce the severity and duration of symptoms. Without treatment, cold sores can take up to 10 days to heal. Prescription antivirals such as Aciclovir and Valaciclovir are effective in speeding up recovery and minimising discomfort.
At 123Meds, you can access cold sore treatments quickly and discreetly with an online consultation.
Aciclovir: Aciclovir (also known as Acyclovir) is an antiviral medication taken to effectively treat cold sore outbreaks. Aciclovir works by stopping the HSV virus from multiplying, which significantly shortens the outbreak duration and accompanying symptoms.
Valaciclovir: Valaciclovir (also known as Valacyclovir) is an antiviral medication used in the treatment of cold sores. Valaciclovir is a precursor of Aciclovir, which means it changes into Aciclovir in the body. This means it stays in the body for longer and does not need to be taken as often as Aciclovir.
What should you do and not do if you have a Cold Sore outbreak?
When experiencing an outbreak of cold sores it’s important to manage it effectively, this is necessary to ease discomfort, speed up the healing process and reduce the risk of passing the virus on.
The Do’s and Don'ts of having cold sores:
- Do: Drink plenty of fluids to avoid dehydration.
- Do: Wash your hands before and after applying the cream.
- Do: Use lip balm with SPF 15 or above.
- Do: Eat cool, soft foods.
- Do: Take painkillers to ease pain and swelling.
- Do not: touch your cold sore.
- Do not: kiss anyone when you have a cold sore.
- Do not: share anything you come into contact with (e.g. cutlery, lipstick).
- Do not: eat salty, acidic food.
- Do not: have oral sex until your cold sore has completely healed.
How do people get cold sores?
Cold sores are caused by the herpes simplex virus (HSV-1) and spread through close contact. This includes kissing or touching someone with a cold sore or sharing items like eating utensils, towels, or washcloths.
How are cold sores treated?
Cold sores cannot be cured, but antiviral medicines like aciclovir, famciclovir, and valaciclovir can make outbreaks less severe and shorter. Over-the-counter creams for pain relief or inflammation can also ease symptoms. For the best results, start treatment as soon as you notice the first signs of a cold sore.
When should I call a doctor about cold sores?
Consult a doctor if you frequently experience cold sores, if a sore doesn’t heal within 7–10 days, or if you have a weak immune system. Seek immediate medical attention if the sore is near your eyes, you experience eye pain or redness, or you show signs of infection such as fever or spreading redness.
Can cold sores spread to other parts of the body?
Yes, HSV-1 can spread to other areas, such as the eyes, lips and face, which can be severe. Avoid touching the sore and always wash your hands after contact.
Can cold sores be prevented?
To prevent spreading cold sores, avoid kissing or sharing personal items during an outbreak. Wash hands frequently and avoid touching the sores.
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