CategoryDetails
Type of DrugPhosphodiesterase type 5 (PDE5) inhibitor.
Health Conditions TreatedErectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH).
Active IngredientTadalafil
Brand NamesCialis, Adcirca (used for pulmonary arterial hypertension).
Available Strengths2.5mg, 5mg, 10mg, and 20mg tablets.
Available AsFilm-coated oral tablets.
Possible Side EffectsCommon: headache, flushing, nasal congestion, indigestion, muscle aches. Rare: priapism, vision changes.
ManufacturersEli Lilly and Company (Lilly UK).

What is Cialis?
Cialis is a trusted prescription medication used to treat erectile dysfunction (ED) and related conditions. Its active ingredient, tadalafil, helps improve blood flow to the penis, ensuring an erection strong enough for sexual activity. This makes it one of the leading options for men seeking an effective and reliable solution for ED.

What is Cialis Used For?

Erectile Dysfunction (ED)
Cialis is primarily prescribed for men who struggle with achieving or maintaining erections during sexual activity.
Benign Prostatic Hyperplasia (BPH)
It helps reduce urinary symptoms like frequent urination, incomplete emptying of the bladder, and weak urinary flow caused by an enlarged prostate.
Combination of ED and BPH
For males with both erectile dysfunction and BPH-related urinary problems, Cialis works especially well.
Pulmonary Arterial Hypertension (PAH)
Under the brand name Adcirca, Cialis is also used to manage PAH by reducing blood pressure in the lungs.
 
At 123Meds, we offer Cialis for the treatment of Erectile Dysfunction only - if you are interested in using Cialis for any other condition, we would advise that you seek further review from your GP to determine whether it is an appropriate treatment option.

How Does Cialis Work?

Cialis works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which regulates blood flow in the penis. By blocking PDE5, Cialis allows for better blood circulation and helps achieve and maintain an erection during sexual arousal.

Detailed Mechanism

Enhances Blood Flow

Cialis relaxes blood vessel walls, improving blood flow, particularly in the pelvic area, which is essential for sexual activity.

Prolonged Effect

Known as the “weekend pill,” Cialis effects can last up to 36 hours, offering more flexibility and less pressure on timing sexual activity.

Targeted Action

It focuses on the penis while minimising the impact on other systems, ensuring effectiveness with fewer side effects.

When Should You Consider Taking Cialis?

Erectile dysfunction (ED) is a common condition that can significantly impact confidence, relationships, and overall quality of life. If you find yourself struggling with ED frequently, it might be time to consider Cialis as a solution. This medication is designed to address both the physical and psychological barriers to achieving and maintaining an erection, helping you take control of your sexual health.

Here are some specific situations when Cialis could be the right choice for you:

Inconsistent or Unsatisfactory Erections- If you find that your erections are not consistent or firm enough for satisfying sexual activity, Cialis may help. Its active ingredient, tadalafil, improves blood flow to the penis, making it easier to achieve and maintain an erection during sexual stimulation.
Lifestyle Changes Haven’t Helped- Many men try to manage ED by adopting healthier habits, such as exercising, reducing stress, quitting smoking, or eating a balanced diet. While these changes can improve overall health, they may not always resolve ED. If these efforts haven’t worked, Cialis can provide the additional support you need.
Psychological Factors Contribute to ED- Anxiety, stress, and performance pressure can often lead to or exacerbate ED. By ensuring reliable physical performance, Cialis can help alleviate the psychological stress associated with ED, boosting your confidence and allowing you to focus on intimacy without worry.
You Prefer a Long-Lasting, Flexible Option- Cialis stands out for its long-lasting effects, which can last up to 36 hours. This extended window of effectiveness provides flexibility and spontaneity, eliminating the need to schedule intimate moments around your medication.

By addressing both the physical and emotional aspects of erectile dysfunction, Cialis empowers men to regain their confidence and improve their intimate relationships.

If ED has been a persistent problem for you or something that has developed suddenly, we would advise that you seek further review from your GP to exclude the presence of an underlying medical condition that could be a contributing factor.

Can You Buy Cialis Over the Counter?

A specific version called Cialis Together is accessible over-the-counter in the UK without a prescription. This medication contains 10mg of tadalafil and is intended for men aged 18 and over experiencing erectile dysfunction. It can be purchased directly from pharmacies, as well as online platforms such as 123Meds. However, other strengths of Cialis, 2.5mg, 5mg and 20mg), require a prescription from a healthcare professional. 123Meds can help determine the best treatment for your needs.

Alternative Medications

If Tadalafil is not suitable or preferred, there are a number of alternatives that may be suitable. Your 123Meds prescriber will look to recommend you a treatment based upon your medical history, including your previous experiences with the use of ED treatments.

Viagra (Sildenafil): Works within 30–60 minutes and lasts 4–6 hours. Best on an empty stomach.

Levitra (Vardenafil): Similar to Viagra, it works within an hour, lasting 4–5 hours. Suitable for those experiencing side effects with other ED medicines.

Spedra (Avanafil): A fast-acting option that works in 15–30 minutes and lasts 4–6 hours. It can be taken with or without food.

Alprostadil: Non-oral option available as injections or suppositories. It directly stimulates erection without relying on arousal.

Taking Cialis correctly ensures its effectiveness and minimises side effects. Follow these directions for safe and optimal use:

Daily Dose- For men who prefer a consistent daily treatment, Cialis is available in low doses of 2.5mg or 5mg. Take it at the same time every day, regardless of planned sexual activity. This option maintains a steady level of the medication in your system, allowing for spontaneity at any time.

On-Demand Dose- If you plan to use Cialis occasionally, the standard dose is either 10mg or 20mg, taken 30 minutes before sexual activity. This dosage provides effectiveness for up to 36 hours, giving you a wide window for intimate moments without the need for precise timing.

With or Without Food- Cialis is versatile and can be taken on an empty stomach or after a meal. Unlike some medications, food does not impact its effectiveness, so you can take it at your convenience.

Avoid Alcohol- While moderate alcohol consumption may not interfere with Cialis, heavy drinking can reduce its effectiveness and increase the likelihood of side effects like dizziness or low blood pressure. Limiting alcohol intake is recommended for the best experience.

By following these guidelines, you can make the most out of Cialis while minimising potential issues. Always consult your doctor or pharmacist for personalised advice tailored to your health and lifestyle.

  • Active Ingredient: Tadalafil (improves blood flow).
  • Inactive Ingredients: Lactose Monohydrate, Magnesium Stearate, Titanium Dioxide, Hypromellose.


Note: Inactive ingredients may vary between manufacturers. Always check the packaging or prescription for specific details and make your prescriber aware if you have any allergies. If you do have any allergies and are unsure whether our treatments are suitable for you, please contact us before taking any medication that has been prescribed.

While Cialis is generally safe, it may cause side effects in some individuals.

Common Side Effects:

  • Headache.
  • Flushing.
  • Indigestion.
  • Nasal congestion.
  • Muscle aches.
  • Dizziness.
  • Back pain.

Rare Side Effects:

  • Priapism: A prolonged erection lasting more than 4 hours—seek immediate medical attention.
  • VisionChanges: Sudden loss of vision is rare but requires immediate medical consultation.
  • Hearing Loss: Sudden loss or decrease in hearing may occur in rare cases.
    Most side effects are mild and temporary, resolving on their own or with reduced dosage.

If any severe or persistent symptoms occur, discontinue use and seek urgent medical evaluation from your GP, NHS111 or A&E as appropriate.

  • What is Cialis?

    Cialis is a prescription medication developed to treat ED, which is the difficulty of achieving or maintaining an erection during sexual activity. It is also prescribed to manage symptoms of benign prostatic hyperplasia (BPH), which is associated with difficulty urinating. The active ingredient in Cialis, tadalafil, aids in improving blood flow to specific areas of the body, thus making it very effective for these conditions.


    At 123Meds, we offer Cialis for the treatment of Erectile Dysfunction only - if you are interested in using Cialis for any other condition, we would advise that you seek further review from your GP to determine whether it is an appropriate treatment option.

  • How does Cialis work?

    Cialis works by inhibiting the phosphodiesterase type 5 (PDE5) enzyme. This is responsible for the regulation of the blood flow in the penis. By inhibiting the PDE5, Cialis increases the blood flow into the penis and relaxes its blood vessels, allowing easy erection during sexual stimulation and helping men to have as well as maintain an erection. It only works during sexual arousal, so this is a natural response toward intimacy.

  • How long does Cialis last?

    One dose of the medicine can last up to 36 hours—due to this effect, Cialis is sometimes referred to as the "weekend pill.". Cialis is also offered in doses of 2.5mg and 5mg, which are designed to be taken daily to allow for complete flexibility and spontaneity.

  • Can women take Cialis?

    No, Cialis is not approved for women. It is manufactured and prescribed only for men suffering from erectile dysfunction or any other similar disorder.

     

  • Is Cialis safe for long-term use?

    Cialis is considered safe for long-term use when used under the supervision and recommendation of a healthcare professional. However, if you have been using ED medicines for a prolonged period of time, we recommend seeing your GP for a review to exclude any underlying health conditions that could be a contributing factor in your ED symptoms.

  • Can I consume alcohol with Cialis?

    While you can drink alcohol in moderation while on Cialis, excessive alcohol drinking can interfere with the medicine's effectiveness. Drinking too much can lower blood pressure, which may increase the risk of side effects like dizziness or fainting. For best results, limit alcohol intake when using Cialis.

  • How long does it take for Cialis to begin working?

    Cialis typically starts working 30 to 60 minutes after ingestion. However, this can vary depending on factors like whether you’ve eaten recently. Unlike some other ED medications, Cialis is not as affected by food, making it a more convenient option for many users.

  • What if I miss a dose of Cialis?

    If you are on a daily dose of Cialis and miss one, take it as soon as you remember unless it is almost time for your next scheduled dose. For as-needed use, you do not need to worry about missing a dose because it is only taken when planning sexual activity.

  • Is Cialis habit-forming?

    No, Cialis is not associated with physical or psychological dependence. It works as a temporary cure for erectile dysfunction by improving blood flow. 

  • What's the difference between Cialis and Viagra?

    Cialis and Viagra are both PDE5 inhibitors used for treating erectile dysfunction, but they are different in several ways:

    • Duration: Cialis lasts up to 36 hours, while Viagra works for 4–6 hours.
    • Onset: Viagra generally starts working within 30–60 minutes, like Cialis.
    • Flexibility: Cialis is available in a range of dosages, allowing for a range of sexual spontaneity, while Viagra is taken as needed.
  • Can Cialis be bought over the counter?

    A specific version called Cialis Together is accessible over-the-counter in the UK without a prescription. This medication contains 10mg of tadalafil and is intended for men aged 18 and over experiencing erectile dysfunction. It can be purchased directly from pharmacies, as well as online platforms such as 123Meds. However, other strengths of Cialis, 2.5mg, 5mg and 20mg) the standard Cialis formulations, which may include different dosages, still require a prescription from a healthcare professional. 123Meds can help determine the best treatment for your needs.

  • Can I take Cialis daily?

    Yes, Cialis is available in low-dose formulations (2.5mg or 5mg) for daily use. This is especially helpful for men who want to maintain readiness for sexual activity at any time without planning around taking medicine. Your 123Meds prescriber can help you determine the right option for your circumstances.

  • Does Cialis have generic options?

    Yes, the generic version of Cialis is known by the name Tadalafil. We also offer generic Tadalafil as a treatment option at 123Meds.

  • Can I take Cialis if I have heart disease?

    Tadalafil can be safe for some patients with heart conditions, but it should not be taken with nitrate medications, as this combination can cause a dangerous drop in blood pressure. Always inform your prescriber about any medical conditions or medicines that you are using to ensure that the prescribed treatment is safe and appropriate.

  • What foods should you avoid taking with Cialis?

    While Cialis can be administered with or without food, you should avoid excessive amounts of grapefruit or grapefruit juice. Grapefruit can interact with Cialis and increase the levels of the medication in your blood, potentially leading to stronger side effects.

  • Does Cialis treat premature ejaculation?

    Cialis is not specifically approved for treating premature ejaculation, but it may help indirectly by improving erectile function. Some men find that having firmer, longer-lasting erections boosts their confidence and delays ejaculation. Treatments for premature ejaculation should not be typically used alongside ED medication, as the combined action of the medication can lead to significant side effects.

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