What is Mebeverine (Generic Colofac) 135 mg Tablets?

Mebeverine is an antispasmodic medicine used to relieve symptoms of irritable bowel syndrome (IBS) and other conditions that cause painful muscle spasms in the gut. Each tablet contains 135 mg of mebeverine hydrochloride. It is usually taken before meals to help reduce abdominal discomfort, cramps, bloating, and changes in bowel habit.

How Does Mebeverine (Generic Colofac) 135 mg Tablets Work?

Mebeverine acts directly on the smooth muscle in the gut. It relaxes the muscle and reduces painful spasms without slowing down the normal movement of the intestines. This helps ease cramps, pain, and bloating often associated with IBS, while allowing the bowel to continue working normally.

Symptoms of IBS

Irritable bowel syndrome can cause a range of ongoing digestive symptoms, including:

Abdominal cramps or stomach pain that may improve after passing stool
Bloating and excess wind
Diarrhoea, constipation, or an alternating pattern of both
Urgency or incomplete emptying of the bowel
Symptoms often flare up during times of stress, after certain foods, or without a clear trigger.

Do not take this medicine if you:

Are allergic to mebeverine or any of the ingredients in the tablet
Are under 18 years old, unless specifically advised by a doctor

Alternative Treatment Options

Other ways to manage IBS and gut spasms include:

• Dietary changes such as increasing fibre, reducing caffeine, or following a low FODMAP diet.
• Over-the-counter remedies for diarrhoea or constipation, depending on symptoms.
• Other prescription medicines such as antispasmodics (e.g. hyoscine butylbromide) or peppermint oil capsules.
• Stress management, exercise, and lifestyle changes.
  
  

Can Mebeverine (Generic Colofac) 135 mg Tablets Be Purchased Over the Counter?

Yes. In the UK, mebeverine 135 mg tablets are available to buy over the counter from pharmacies. A pharmacist will check your symptoms and medical history to ensure the medicine is suitable for you before supply

• The usual adult dose is one 135mg tablet three times daily.
• Tablets should be swallowed whole with water, 20 minutes before meals. Do not chew or crush.
• As symptoms improve, your prescriber may reduce the dose.
• Always follow the instructions provided by your prescriber or pharmacist.
  
  

Warnings and precautions

Speak to your doctor or prescriber before taking mebeverine if you:

Have unexplained weight loss, fever, or blood in stools
Have persistent constipation or vomiting
Have recently developed new or severe abdominal pain
Are pregnant or breastfeeding (only take if advised by a doctor)

Mebeverine is generally well tolerated, but side effects may include:

• Mild skin reactions such as rash or itching
• Rare allergic reactions such as swelling of the face, lips, or throat, or difficulty breathing (seek urgent medical attention)