CategoryDetails
Type of MedicinePrescription-only migraine treatment (triptan / 5-HT₁ receptor agonist)
Health Conditions Prescribed ForAcute migraine attacks with or without aura in adults
Active IngredientsRizatriptan benzoate (equivalent to 10mg rizatriptan per tablet)
Brand NamesMaxalt, Maxalt Melt
Available Strengths10mg
Available AsOrodispersible tablets (wafers that dissolve on the tongue)
Possible Side EffectsDizziness, drowsiness, nausea, dry mouth, flushing, heaviness in limbs, chest discomfort
ManufacturersMerck Sharp & Dohme (UK) Limited

What is Maxalt Melt? 

Maxalt Melt 10 mg orodispersible tablets are a prescription-only medicine used for the sudden treatment of migraine attacks, with or without aura, in adults. Each tablet contains rizatriptan benzoate, which is a type of medicine called a triptan. It works by reducing the size of blood vessels in the brain that are thought to cause migraine pain and related symptoms.

Maxalt Melt is made to dissolve on the tongue without water, making it especially helpful for those who feel sick during migraine attacks. It should be taken as soon as a migraine starts and is not meant to stop future migraines.

What is Maxalt Melt Used For? 

Sudden Treatment of Migraine Attacks: Maxalt Melt is prescribed to treat the headache stage of sudden migraine attacks in adults, with or without aura.
Relief from Related Migraine Symptoms: It helps ease common migraine signs such as feeling sick, vomiting, and sensitivity to light and sound.
Suitable for Quick and Easy Use: Because it dissolves on the tongue, it is very useful for migraine sufferers who feel sick or have trouble swallowing during an attack, giving fast relief without needing water.

At 123Meds, we supply Maxalt Melt only for treating sudden migraine attacks. If you are thinking of using Maxalt Melt for any other medical reason, we recommend speaking to your general practitioner to see if it is the right treatment for you.

How Maxalt Melt Works 

Maxalt Melt contains rizatriptan, a type of medicine called a triptan, used to ease migraine attacks. It works by fixing the changes in the brain’s blood vessels that cause migraine symptoms.

Mechanism of Action: 

Makes Widened Blood Vessels Smaller: Rizatriptan works on serotonin (5-HT₁B/₁D) receptors in the brain. This makes the blood vessels around the brain that have widened get smaller, which helps reduce migraine pain.
Stops Pain Signals: It stops chemicals that carry pain messages in the brain, lowering headache strength and related symptoms.
Reduces Nerve Swelling: Maxalt Melt helps lessen the swelling of nerves around the brain’s blood vessels, which adds to easing migraine pain.

When is Migraine Attack Confirmed, and Medication Needed? 

A migraine attack is usually confirmed when someone has a moderate to severe headache, often on one side of the head, with signs like feeling sick, being sick, or sensitivity to light and sound. 

Some people may notice warning signs, called an aura, which can include sight problems or tingling feelings. Medicine like Maxalt Melt is usually needed when these signs start to get in the way of everyday activities or get worse. It should be taken at the first sign of a migraine for the best relief.

Physical causes of Migraine: 

Hormonal Changes: Changes in hormone levels, especially oestrogen, can cause migraines in some people around menstruation, pregnancy, or menopause.
Irregular Sleep Patterns: Lack of sleep or too much sleep can lead to migraine attacks in sufferers.
Dietary Triggers: Some foods and drinks, such as mature cheese, chocolate, and caffeinated drinks, can also cause migraines.

Psychological causes of Migraine: 

Stress and Anxiety: High levels of emotional stress or ongoing anxiety can increase the chance of migraine attacks.
Mental Fatigue: Long mental strain or overwork can act as a psychological trigger for migraines.

Symptoms of Migraine: 

Severe headache pain: Often throbbing, on one side.
Nausea and vomiting: Occurs with many migraine attacks.
Sensitivity to light and sound: Discomfort worsens with bright lights.

If migraine symptoms continue for weeks or worsen, it is important to seek medical advice.

A prescriber or physician will identify the condition based on your medical history and symptoms. Depending on the main cause, treatment options may include prescribed medication such as Maxalt Melt to ease migraine attacks. Other treatments or therapies may also be suggested based on individual requirements. It is vital to speak with a medical practitioner to choose the most suitable and effective treatment plan.

Can Maxalt Melt 10mg orodispersible tablets Be Purchased Over the Counter? 

No, in the UK, Maxalt Melt 10 mg orodispersible tablets cannot be bought without a prescription. They are only available on prescription and must be obtained with a valid prescription from a prescriber or medical practitioner.

To get Maxalt Melt, you need a medical check-up, either face-to-face with your general practitioner or through an approved online service. Once you have a prescription, you can collect the medicine from a registered pharmacy. It is important to speak to a medical practitioner to check if Maxalt Melt is the right treatment for you.

Alternative Medications 

Alternative medicines may be used if Maxalt Melt is unsuitable, ineffective, or not tolerated. These options include other triptans and non-triptan therapies, each with its own time to work and possible side effects.

Sumatriptan (Imigran): Sumatriptan is a common triptan available as tablets, a nasal spray, or an injection. It targets 5-HT₁B/₁D receptors to relieve migraine pain within two hours. Imigran is often chosen for its different forms, allowing people to pick the most convenient way based on symptom severity and tolerance.
Zolmitriptan (Zomig): Zolmitriptan is also another triptan available as tablets or orodispersible wafers. It usually provides relief within one to two hours and may be preferred by those who feel sick, as the wafer melts on the tongue without water. Zomig’s quick absorption can be helpful when migraines develop rapidly.
Naproxen (Naprosyn): Naproxen is a non-steroidal anti-inflammatory medicine (NSAID) used to ease mild to moderate migraine pain and reduce inflammation. It is available over the counter or by prescription and is often used in combination with triptans. Naproxen may help people who need anti-inflammatory action alongside pain relief.

If you are unsure about which treatment is best for you, please speak to your 123Meds prescriber for personalised advice and guidance.

How to Take Maxalt Melt? 

Timing: Take Maxalt Melt as soon as you notice migraine symptoms for the most effective relief.

Dosage: Adults should take one 10 mg orodispersible tablet of Maxalt Melt at the start of migraine symptoms. If symptoms continue or come back, a second 10 mg tablet may be taken at least two hours after the first dose. Do not take more than three 10 mg tablets (30 mg) in 24 hours. Maxalt Melt is not meant for under-18s or for regular migraine prevention. For people over 65 or those with mild to moderate liver problems, a lower dose of 5 mg may be considered based on clinical judgement. Always follow your prescriber’s instructions and do not change the dose yourself to avoid overdose.

With Food: Taking Maxalt Melt with food may slow its absorption and make it less effective. For best relief, it’s usually advised to take the tablet on an empty stomach or at least one hour before or two hours after meals to ensure it works quickly.

Avoid Alcohol: Drinking alcohol while taking Maxalt Melt may trigger migraines and increase the chance of side effects such as dizziness or drowsiness. It’s sensible to avoid alcohol when you take this prescribed medication to prevent reduced effect and increased adverse reactions.

If you missed a dose of Maxalt Melt, do not take an extra dose to make up for it. Instead, wait until the next migraine attack to take the medication if needed.

Maxalt Melt includes both active and inactive ingredients that work together to ease migraine symptoms.

Active Ingredient:

The active ingredient in Maxalt Melt is rizatriptan benzoate, which works by making the blood vessels in the brain narrower and reducing swelling, helping to ease migraine pain and related symptoms.

Inactive Ingredients:

Inactive ingredients such as aspartame, mannitol, and povidone help to form the tablet, keep it stable, and let it dissolve quickly on the tongue.

Always read the patient information leaflet (PIL) in your pack for the complete list of ingredients, and to check for any you might be allergic to.

Like all prescribed medications, Maxalt Melt may cause side effects, although not everyone will have them. It is important to be aware of possible reactions and seek help from a medical practitioner if you have any worries.

Common Side Effects: 

Dizziness: Feeling light-headed or unsteady may happen, particularly when standing up fast.
Drowsiness: Some people feel extra sleepy or tired after taking the prescribed medication.
Dry Mouth: A dry sensation in the mouth is often reported.
Nausea: Mild sickness or an upset stomach can occur after taking the dose.
Fatigue: Feeling unusually weak or tired is frequently reported.
Flushing: Reddening or warmth of the skin, especially on the face and neck, may happen.
Chest Tightness: A slight feeling of pressure or heaviness in the chest can be experienced.
Tingling or Numbness: Some users report pins and needles or numbness, especially in the hands or feet.

Less Common but Serious Side Effects: 

Severe Allergic Reaction: Signs include swelling of the face, lips, tongue, or difficulty breathing, and need immediate medical help.
Chest Pain or Abnormal Heartbeat: If you have severe chest discomfort or an odd heartbeat, seek urgent medical assistance.
Persistent or Severe Headache: A headache that gets worse or lasts longer than normal after taking Maxalt Melt should be checked by a medical practitioner.

If you experience severe or ongoing side effects such as chest pain, sudden vision changes, or intense dizziness, you should seek immediate medical help from your general practitioner, NHS111, or A&E to prevent complications. Do not ignore strange or worrying symptoms, as these may be medical emergencies needing prompt attention.

Before starting Maxalt Melt, please make sure you have told your prescriber about any existing medical conditions so they can decide on the most suitable treatment and dosage for you.

  • What is Maxalt Melt used for?

    Maxalt Melt 10 mg orodispersible tablets are prescribed for the sudden treatment of migraine attacks, with or without aura, in adults. Each wafer dissolves on the tongue, giving fast relief from headache and related symptoms such as nausea and light sensitivity.

  • How does Maxalt Melt work to treat migraines?

    Rizatriptan, the active ingredient in Maxalt Melt, works on 5-HT₁B/₁D receptors to make widened blood vessels in the brain narrower, reduce swelling around nerves, and stop pain signals from being sent. This combined effect eases migraine headaches and related symptoms.

  • How should I take Maxalt Melt tablets?

    Place one 10 mg Maxalt Melt wafer on the tongue at the first sign of a migraine, allowing it to dissolve without water. If symptoms return after two hours, a second 10 mg dose may be taken, but do not exceed 30 mg within 24 hours.

  • Can I buy Maxalt Melt over the counter in the UK?

    No, Maxalt Melt 10 mg orodispersible tablets cannot be bought without a prescription in the UK. They are prescription-only medicines, needing a proper prescription from a general practitioner or approved online prescriber, and must be given by a registered pharmacy.

  • What are the common side effects of Maxalt Melt?

    Common side effects of Maxalt Melt may include feeling light-headed, drowsiness, dry mouth, and mild nausea. Some people also experience tiredness, flushing, a tight feeling in the chest, or tingling and numbness in the hands or feet, which usually pass without specific treatment.

  • Are there any serious side effects of Maxalt Melt I should watch for?

    Although rare, serious side effects can occur, such as a severe allergic reaction with swelling of the face or throat and trouble breathing. If you have chest pain or an irregular heartbeat, or if your headache worsens or does not go away, you should seek urgent help.

  • Can I take Maxalt Melt if I am pregnant or breastfeeding?

    There is limited information about using Maxalt Melt during pregnancy or while breastfeeding; it should only be used if the potential benefit outweighs any possible risk. Speak to your general practitioner or prescriber before use to check if it is suitable for you.

  • How quickly does Maxalt Melt start working?

    Maxalt Melt usually begins to ease migraine symptoms within 30 to 60 minutes, though some people may feel relief even sooner. It is generally fully effective within two hours of taking the wafer, depending on individual factors and how severe the migraine is.

  • Can I take Maxalt Melt with food, or should I take it on an empty stomach?

    Maxalt Melt is best taken on an empty stomach because food can slow how quickly it works and make it less effective. If you cannot, wait at least one hour after eating or take it two hours before your next meal before placing the wafer on your tongue for the best relief.

  • Is Maxalt Melt safe to use with other migraine medications?

    Do not use Maxalt Melt with other triptans or ergot-based migraine treatments within 24 hours, as this can raise the risk of serious heart problems. Always tell your prescriber about any current migraine-prescribed medication before you start Maxalt Melt to avoid interactions.

  • Can I drink alcohol while taking Maxalt Melt?

    Drinking alcohol can make migraine symptoms worse and increase the chances of side effects like dizziness or drowsiness when you take Maxalt Melt. It is best to avoid alcohol around the time you use this prescribed medication to keep it working well and reduce unwanted effects.

  • How many Maxalt Melt tablets can I take in 24 hours?

    Adults can take up to three 10 mg tablets (30 mg total) in 24 hours. Take the first wafer when a migraine starts and, if needed, take a second dose at least two hours later. Do not take more than three wafers in one day to avoid overdose risks.

  • Can children or teenagers use Maxalt Melt?

    Maxalt Melt is not advised for anyone under 18, as its safety and how well it works in children and teenagers is not known. A prescriber will look at other treatments that are better suited for younger people with migraines.

  • What should I do if I miss a dose of Maxalt Melt?

    Maxalt Melt is taken at the start of a migraine and does not have a regular dosing schedule. If you miss a dose because your migraine has gone away, do not take an extra tablet. Instead, wait until your next migraine and use the wafer for that attack.

  • Can Maxalt Melt be used to prevent migraines?

    No, Maxalt Melt is only for sudden migraine treatment and should not be used to prevent migraines. For migraine prevention, your general practitioner may suggest other treatments such as beta-blockers, anticonvulsants, or anti-CGRP therapies based on your medical history.

  • Can Maxalt Melt cause allergic reactions?

    Yes, although rare, Maxalt Melt can cause allergic reactions. Signs may include rash, itching, swelling of the face, lips or tongue, and trouble breathing. If you have any of these symptoms, seek immediate medical help.

Our 5-Point Safety Guarantee

We focus on trust, privacy, and expert service in online medication ordering.

GPHC and MHRA Regulated Pharmacy icon

GPHC and MHRA Regulated Pharmacy

Regulated by all necessary UK regulatory bodies

UK qualified Pharmacists icon

UK qualified Pharmacists

All consultations reviewed by UK pharmacists

Authentic Medication icon

Authentic Medication

Sourced from approved suppliers only

Customer Care icon

Customer Care

Customer care team available via email or phone

Trusted by Thousands icon

Trusted by Thousands

Thousands of satisfied customers

UK Prescribers &<br>pharmacists icon
UK Prescribers &
pharmacists
100% Discretion on all<br>consultations & orders icon
100% Discretion on all
consultations & orders
Express next day<br>delivery before 3:30PM icon
Express next day
delivery before 3:30PM
Online Prescription<br>Available Now icon
Online Prescription
Available Now